Migraine:
Stopping an attack, understanding aura & prevention

At a glance

FrequencyOne of the most common neurological conditions — around 10–15% of adults in Germany are affected, with women about three times as often as men
Other namesMigraine attack, hemicrania, "migraine with/without aura"
Key symptomSudden, often one-sided, pulsating, throbbing headache, worsened by movement, frequently with nausea as well as sensitivity to light and noise
DiagnosisClinical, based on the typical attack pattern (headache diary) — imaging only in the presence of warning signs
First lineAcute: a triptan or painkiller plus an anti-nausea medication; for prevention, prophylactic medication and non-drug measures
ICD-10G43.9 (Migraine, unspecified)

Attacks and medications in one place

Keep your headache diary in brite, identify your triggers and get reminded about your prophylaxis — with a clear overview for your next doctor's appointment. Free of charge.

Track attacks

Table of contents

  1. What is migraine?
  2. With vs. without aura & the phases of an attack
  3. Symptoms
  4. Causes & triggers
  5. Diagnosis & attack diary
  6. Treatment: acute treatment of an attack
  7. Treatment: prophylaxis explained
  8. Medication-overuse headache
  9. Everyday life & warning signs
  10. How brite helps you
  11. FAQ
  12. Related topics
Note A sudden, never-before-experienced "thunderclap headache", a headache with fever and a stiff neck, or one with paralysis needs immediate assessment — when in doubt, call the emergency number 112. This is not an ordinary migraine.

1. What is migraine?

Migraine is not an ordinary type of headache but a distinct neurological condition. It is characterised by recurring attacks with a usually one-sided, pulsating, throbbing headache that worsens with physical activity and is often accompanied by nausea as well as a pronounced sensitivity to light and noise. Left untreated, a single attack lasts between 4 and 72 hours — from a few hours up to three days.

Unlike a simple tension headache, during an attack those affected are often barely able to work or function. Many retreat to a darkened, quiet room and wait out the worst lying down. Migraine is therefore not only painful but one of the world's leading causes of years of healthy life lost in middle adulthood — precisely during the most productive years.

What happens in the brain is far better understood today than it once was. During an attack, there is a temporary overexcitability of the brain and an activation of the so-called trigemino-vascular system — a network of nerves that supplies the blood vessels of the meninges. In the process, messenger substances are released, above all a protein called CGRP, which dilates vessels and transmits the pain. It is precisely this messenger that modern migraine medications target. Migraine is therefore not a "sign of weakness" and not purely a consequence of stress, but has a clear biological basis — it is very treatable, but not curable in the sense of disappearing permanently.

The good news Migraine can today be treated effectively on two levels: a well-chosen acute therapy can often stop a single attack within one to two hours, and prophylaxis markedly reduces the number and severity of frequent attacks. Many people thereby regain a large part of their everyday life.

2. With vs. without aura & the phases of an attack

Broadly, two main forms are distinguished: migraine without aura (formerly "common migraine") and migraine with aura (formerly "classic migraine"). Around two thirds of those affected have no aura, while a third experience one at least occasionally.

An aura is a temporary neurological disturbance that usually precedes or accompanies the headache. It typically develops slowly over 5 to 20 minutes and does not, as a rule, last longer than 60 minutes. Visual disturbances are the most common: flickering, flashes of light, zigzag lines or a blind spot that slowly spreads across the field of vision. Less commonly, there is a tingling or numbness that slowly "travels" from the hand up the arm to the face, or word-finding difficulties. What is crucial for distinguishing it from a stroke is that a migraine aura builds up slowly and then resolves completely — a stroke, by contrast, begins suddenly.

Aura for the first time? Always get it checked A first-time aura, sudden visual disturbances or numbness should always be assessed by a doctor — above all to rule out a stroke. Only once the pattern is reliably known can it be safely attributed to migraine.

An attack often runs through several phases, which not everyone experiences with the same intensity. Knowing them means you can counteract earlier:

PhaseTimingTypical signs
Warning phase (prodrome)Hours to 2 days beforehandYawning, food cravings, irritability, difficulty concentrating, neck stiffness
Aura5–60 minutes before/with the painFlickering, zigzag lines, tingling, speech disturbance (only in about one third)
Headache phase4–72 hoursThrobbing, often one-sided pain, nausea, aversion to light and noise
Resolution & exhaustion (postdrome)Up to 1–2 days afterwards"Headache hangover", tiredness, exhaustion, low mood
Table scrollable to the right

Knowing about the warning phase is practically valuable: those who recognise their own early signs — for example increased yawning or a craving for sweets — can better time rest, fluids and taking medication in good time. The treatment window for acute medications is decisive: as early as possible in the headache phase, but not yet during the aura (more on this in the treatment chapter).


3. Symptoms

The migraine headache has a fairly typical pattern that sets it apart from other types of headache. Not every feature has to be present in every attack, but the combination is characteristic:

  • Location: frequently one-sided (though it can switch sides or be bilateral), often around the temple, forehead or behind the eye
  • Character of the pain: pulsating, throbbing, pounding — in time with the heartbeat
  • Worsening with movement: climbing stairs, bending down or everyday activity makes the pain worse — hence the retreat to bed
  • Accompanying nausea up to vomiting
  • Aversion to light and noise (photophobia and phonophobia), often also a sensitivity to smells
  • Duration: 4 to 72 hours untreated

By way of comparison: a tension headache feels more dull and pressing, sits like a "band" around the whole head, is bilateral and is not made worse by movement — nausea and marked light sensitivity are usually absent. This distinction matters because the treatment differs considerably.

In children, migraine looks different In children and adolescents the attacks are often shorter, more frequently bilateral and more strongly marked by abdominal pain, nausea and pallor. The headache is not always to the fore — which is why migraine is easily overlooked in childhood.

4. Causes & triggers

The underlying predisposition to migraine is to a large extent genetic — migraine tends to run in families. Those affected bring with them an increased sensitivity of the brain to stimuli; their nervous system reacts more sensitively to fluctuations from within and without. On this basis, certain triggers (triggers) can set off a single attack. It is important to understand: triggers are not the cause of migraine, only the spark — and they are highly individual.

Commonly cited triggers include:

  • Stress — or precisely the easing of stress ("weekend" or "let-down" migraine)
  • A changed sleep rhythm — too little, but also too much sleep
  • Skipped meals and the resulting fluctuating blood sugar
  • Hormonal fluctuations — especially the drop in oestrogen before menstruation (menstrual migraine)
  • Dehydration and not drinking enough
  • Changes in the weather and changes in air pressure
  • Alcohol (red wine above all) and, in part, certain foods
  • Strong sensory stimuli — bright or flickering light, loud noises, intense smells

The most important protective factor is a regular rhythm: even sleep and mealtimes, adequate fluids and a mindful approach to stress. That sounds unspectacular, but it is one of the most effective levers of all. When it comes to diet, sobriety pays off rather than strict lists of prohibitions: only a few people really have a reliable food trigger. Instead of cutting out many foods across the board, a headache diary helps to tell real triggers from supposed ones.


5. Diagnosis & attack diary

A migraine diagnosis is as a rule made clinically — that is, from the medical history and the typical pattern of attacks alone, without any device being able to "prove" it. Imaging (MRI/CT) is not necessary for a typical migraine and is only arranged in the presence of warning signs or an atypical course.

By far the most important tool is a headache diary, or attack diary. It helps to confirm the diagnosis, identify triggers and later assess the success of treatment. For each attack, note:

  • Date and duration of the attack as well as the time of day it began.
  • Pain intensity (e.g. on a scale of 0 to 10) and the location of the pain.
  • Accompanying symptoms such as nausea, aversion to light/noise or an aura.
  • Possible triggers: sleep, stress, meals, menstruation, weather.
  • Medication, dose and time taken — and whether it helped. This is at the same time the basis for spotting overuse early.

Diagnosing migraine without aura typically requires at least five such attacks with the matching features; with aura, two are enough. You don't need to memorise these numbers — what matters is that a well-kept diary makes it considerably easier for the practice to classify things. The doctor will additionally examine the nervous system and ask specifically about warning signs that argue against a harmless migraine (see chapter 9).

6. Treatment: acute treatment of an attack

The aim of acute therapy is to stop a single attack as quickly and completely as possible. Two principles decide whether it succeeds: the right substance and the right treatment window. As a rule of thumb: as early as possible in the headache phase, at an adequate dose and not hesitantly in small portions. Anyone who waits too long, until the pain is "really bad", wastes effectiveness.¹

A proven trick against the nausea and the slowed stomach activity during an attack: take an anti-nausea medication about 15 minutes before the actual painkiller. It not only relieves the nausea but also improves the absorption of the painkiller that follows.

Level 1 Mild to moderate attacks
Anti-nausea medication (e.g. Metoclopramide)
Taken about 15 minutes before the painkiller. It relieves nausea and stimulates stomach movement so that the painkiller is absorbed better. Domperidone is an alternative.
Painkiller (e.g. Ibuprofen)
NSAIDs such as Ibuprofen (e.g. 400–600 mg) or Acetylsalicylic acid work well for milder attacks. Important: dose high enough and take early. Metamizole is a further option, particularly when NSAIDs are not tolerated.
Level 2 Moderate to severe attacks — triptans
Triptans (e.g. Sumatriptan)
The specific migraine medications. They act in a targeted way on the trigemino-vascular system and stop the attack, rather than merely dampening the pain. Sumatriptan is the classic; there are further active substances (e.g. Zolmitriptan, Rizatriptan, Naratriptan) with differing speed and duration of action.
Treatment window & formulation
Take triptans early in the headache phasenot during the aura, but only once the headache sets in. If nausea is severe, a nasal spray or a melt-in-the-mouth tablet helps. If an attack initially responds but the pain then returns, a second dose is possible after at the earliest 2 hours.
When triptans are not suitable
In severe cardiovascular disease (for instance after a heart attack or stroke) triptans are as a rule not suitable, because they constrict blood vessels. In such cases and where they are not tolerated there are newer alternatives — that belongs in a doctor's hands.
Not on too many days As effective as acute medications are — if they are taken on too many days a month, they risk causing headaches themselves (medication-overuse headache, see chapter 8). Hence the 10/20 rule, and frequent attacks are a signal to think about prophylaxis.

7. Treatment: prophylaxis explained

While acute therapy tackles the single attack, prophylaxis is meant to reduce the number, severity and duration of attacks over the long term. It is not a treatment for an emergency but is taken daily and on an ongoing basis. Prophylaxis is usually considered when you have three or more attacks a month, when the attacks are particularly severe or long, when acute medications do not work well enough or when there is a looming risk of overuse.¹,²

Important for setting expectations: prophylaxis does not work immediately. The effect builds up over 6 to 8 weeks, and the dose is usually increased slowly. Even a halving of the number of attack days counts as a success — not their complete disappearance. Patience therefore pays off, and the headache diary is the best way to judge the success objectively.

Classic Established prophylactic substances
Beta blockers (e.g. Metoprolol, Propranolol)
Originally blood-pressure medications, they are among the best-evidenced migraine prophylactics. Particularly suitable when high blood pressure is also present. Note: they can cause tiredness and lower the pulse.
Anticonvulsants (e.g. Topiramate)
Originally an epilepsy medication with good effect against migraine. Possible side effects are tingling in the hands/feet, difficulty concentrating and weight loss. Not suitable in pregnancy.
Amitriptyline (Amitriptyline)
A low-dose antidepressant that is especially helpful when a tension headache, sleep disturbances or a depressed mood are also present. Taken in the evening, it can cause tiredness at first.
Modern Targeted & non-drug prophylaxis
CGRP antibodies
A newer class of substances that specifically blocks the messenger CGRP or its receptor. It is given as an injection under the skin (usually monthly) and comes into question above all when classic prophylactics have not worked or were not tolerated.
Non-drug methods
Regular endurance exercise, relaxation techniques (e.g. progressive muscle relaxation), biofeedback and behavioural therapy for stress management are well supported by science and work best in combination with drug prophylaxis.
Regularity as the foundation
Fixed sleep and mealtimes, drinking enough and taking breaks are the foundation of any prophylaxis. They cost nothing, have no side effects and enhance the effect of all other measures.

Which prophylaxis fits depends on the number of attacks, any accompanying conditions and your life situation — for instance if you wish to have children, or have high blood pressure or sleep problems. This is a joint decision with the practice. Side effects at the start are no reason to quietly stop: they often ease off, or another substance is a better fit.

Keep acute and preventive therapy under control

brite reminds you about your daily prophylaxis, counts your attack and medication days and makes your progress visible for your next doctor's appointment.

  • Reminders to take your daily prophylaxis
  • Attack and medication days at a glance
  • Interactions checked
Create a medication plan

8. Medication-overuse headache

A particularly important but often overlooked problem: if acute medications and painkillers are taken too frequently, they can themselves cause a constant headache — the medication-overuse headache (MOH). Paradoxically, it arises precisely through the very medications that are supposed to help, and it is one of the most common reasons why episodic migraine turns into an almost daily one.

The rule of thumb against it is easy to remember and is called the 10/20 rule:

Medication groupLimit per monthExamples
Triptans, opioids, combination painkillerson at most 10 daysSumatriptan & other triptans, combination products with caffeine
Simple painkillers (NSAIDs/non-opioids)on at most 20 daysIbuprofen, Acetylsalicylic acid, Paracetamol, Metamizole
Table scrollable to the right

In short: triptans and combination products on no more than 10 days, simple painkillers on no more than 20 days a month — and this over more than three months. Anyone regularly above this risks an overuse headache. A warning sign is when the number of headache days creeps up and you reach "just to be safe" for a tablet more and more often.

The good news: MOH can resolve. The most important step is to end the overuse — the so-called medication break. This works best with medical support and often together with starting prophylaxis, which paves the way out of the vicious circle. This is exactly where keeping a complete count of medication days pays off: only those who know their intake days notice a looming overuse in good time.


9. Everyday life & warning signs

The greatest part of dealing with migraine takes place in everyday life. A few habits make a real difference between frequent and rare attacks:

  • Keep a diary: record attacks, triggers and medication days — the basis for recognising patterns and avoiding overuse.
  • Keep a rhythm: fixed sleep and mealtimes, drink enough, plan in breaks — including at the weekend.
  • Treat early and correctly: take your acute medication in good time, at an adequate dose and within the 10/20 limits.
  • Exercise as prophylaxis: regular, moderate endurance exercise demonstrably reduces the number of attacks.
  • Don't give up on prophylaxis too soon: it needs 6–8 weeks before it works.

As distressing as a migraine attack is — it is not in itself dangerous. There are, however, headaches behind which lies a serious cause requiring urgent treatment. The following warning signs (red flags) argue against a harmless migraine and need immediate assessment.

Call the emergency number 112 immediately — this is not an ordinary migraine Dial the emergency number 112 without delay in the case of a sudden, extremely violent "thunderclap" headache that reaches its maximum within seconds; a headache with fever and a stiff neck; neurological deficits such as paralysis, speech disturbances or persistent visual disturbances that do not fit the known aura pattern; the first or worst headache of your life; and a headache after an accident/fall or with a seizure and clouding of consciousness. When in doubt, always err on the side of getting it checked once too often.

Even without an emergency: if the character of your headaches changes markedly, if they appear for the first time after the age of 50 or become ever more frequent despite treatment, you should have this assessed by a doctor.

Recognise your triggers over time

Record in brite when attacks occur and what preceded them — so patterns become visible that stay hidden in your head alone.

Start a diary

How brite helps you with migraine

Migraine isn't treated with a single tablet but with a system of acute therapy, prophylaxis and avoiding overuse. That only succeeds if you keep an eye on attacks, triggers and medication days. That is exactly what brite supports you with.

  • Intake reminder — your daily prophylaxis (e.g. beta blocker, Topiramate or Amitriptyline) on time and without gaps, so it can develop its effect. Set up a reminder
  • Health history — document attacks, pain intensity, triggers and medication days as a headache diary and bring it as a chart to your appointment. Track your history
  • Interaction check — spots critical combinations, such as triptans together with certain antidepressants, and keeps an eye on the 10/20 limit of your medication days. Check now
  • Digital medication plan — your acute medication and prophylaxis clearly laid out for your GP, neurology and pharmacy. To the medication plan
Start now for free
brite App

FAQ: Common questions about migraine

What is decisive is to treat early and at an adequately high dose. For milder attacks, NSAIDs such as Ibuprofen work; for moderate to severe attacks, specific triptans such as Sumatriptan. An anti-nausea medication about 15 minutes beforehand relieves nausea and improves the absorption of the painkiller. The treatment window is important: as early as possible at the start of the headache phase, not only once the pain is very severe.
Triptans are best taken early in the headache phase, that is as soon as the headache begins — not yet during the aura. In the pure aura phase they tend, in experience, to work less well. If the pain returns after an initial improvement, a second dose is possible after at the earliest two hours.
In migraine with aura, temporary neurological disturbances precede the headache — usually visual disturbances such as flickering or zigzag lines, less commonly tingling or speech disturbances. This aura builds up slowly over minutes and resolves completely within an hour. Around two thirds of those affected have no aura. A first-time aura should always be assessed by a doctor in order to rule out a stroke.
Migraine is typically one-sided, pulsating and throbbing, worsens with movement and is often accompanied by nausea as well as aversion to light and noise. A tension headache feels dull and pressing, sits like a band bilaterally around the head, does not worsen with movement and usually comes without nausea. A headache diary helps to tell the two apart reliably.
If acute medications and painkillers are taken too frequently, they can themselves cause an almost daily headache. The 10/20 rule applies: triptans and combination painkillers on no more than 10 days a month, simple painkillers such as Ibuprofen on no more than 20 days. Anyone regularly above this risks an overuse headache. It can resolve, usually through a medically supervised medication break and the start of prophylaxis.
A preventive long-term therapy is usually considered when you have three or more attacks a month, when the attacks are particularly severe or long, when acute medications do not work well enough or when overuse is looming. The options include established substances such as beta blockers, Topiramate or Amitriptyline as well as modern CGRP antibodies. Prophylaxis does not work immediately but builds up over six to eight weeks.
Regular meals and drinking enough are more important than cutting out individual foods. Only a few people really have a reliable food trigger; more often, skipped meals and fluctuating blood sugar set off attacks. Instead of many prohibitions, a headache diary helps to tell real triggers from supposed ones. Alcohol, red wine above all, is a common trigger.
A typical migraine attack is certainly very distressing, but not in itself dangerous. Caution is warranted with warning signs: a sudden, extremely violent thunderclap headache, a headache with fever and a stiff neck, neurological deficits outside the known aura pattern, or the first or worst headache of your life. In these cases, call the emergency number 112 immediately — it may point to a serious other cause.
Migraine is a chronic predisposition that can change over the course of life. In many women it improves after the menopause; in others, calmer and more intense phases alternate. It cannot be cured in the sense of disappearing permanently, but the attacks can often be kept very well in check through acute therapy, prophylaxis and a regular lifestyle.

11. Related topics

Sources

  1. DGN/DMKG S1 guideline: Therapy of the migraine attack and prophylaxis of migraine (2022). German Society of Neurology / German Migraine and Headache Society. awmf.org
  2. German Migraine and Headache Society (DMKG). dmkg.de
  3. gesundheitsinformation.de (IQWiG): Migraine. gesundheitsinformation.de
  4. International Classification of Headache Disorders (ICHD-3). ichd-3.org
Medical disclaimer: This article is for general information and does not replace medical advice, diagnosis or treatment. Migraine medications, and prophylaxis in particular, should only be started, changed or stopped after consulting a doctor. In the case of a sudden "thunderclap" headache, a headache with fever and neck stiffness, neurological deficits or the first or worst headache of your life, call the emergency number 112 immediately. Last updated: July 2026.