Osteoarthritis: Symptoms, Affected Joints and What Really Helps

At a glance

What is it? The most common joint disease: the joint cartilage wears down, which causes pain and stiffness.
Who does it affect? The risk rises with age, often from 50. Younger people can be affected too, after injuries or overuse.
Key symptoms Start-up pain after rest, pain on loading, brief morning stiffness, grinding in the joint.
Common joints Knee, hip and hands, and often the spine.
Treatment Exercise, weight loss, painkillers from gel to tablet, and a joint replacement if needed.
ICD-10 M15 to M19 (depending on the joint)

What is osteoarthritis?

Osteoarthritis is the most common joint disease in the world. The joint cartilage, which covers the ends of the bones and acts as a shock absorber, gradually wears down. As the cartilage thins, the bones rub against each other more. The result is pain, stiffness and, over time, reduced mobility.

Unlike pure inflammation (arthritis), osteoarthritis is mainly about wear. The two can overlap, though: an irritated joint with signs of inflammation is called activated osteoarthritis. Worth knowing: many people show signs of wear on an X-ray without feeling any symptoms. Conversely, the extent on the image does not always say much about the level of pain.

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Causes and risk factors

Osteoarthritis usually develops from a combination of several factors. The main ones are:

  • age and the general wear over the years.
  • excess weight, which puts a lot of strain on the knees and hips in particular.
  • previous injuries such as a torn cruciate ligament, meniscus damage or a fracture.
  • malalignment such as knock knees or bow legs.
  • heavy one-sided strain through work or sport.
  • a family tendency, especially with hand osteoarthritis.

Symptoms of osteoarthritis

Osteoarthritis has a typical pain pattern that sets it apart from other joint complaints:

  • Start-up pain: the first steps after getting up or after sitting for a while hurt, then it eases.
  • Pain on loading: pain when walking, climbing stairs or carrying.
  • brief morning stiffness that usually eases within a few minutes (generally under 30 minutes).
  • grinding or crunching in the joint.
  • reduced mobility of the joint.

In advanced stages the pain can also occur at rest or at night. You can read more on the page Joint pain.

Telling it apart from inflammation If the morning stiffness lasts well over half an hour, or if several small joints are affected at the same time, swollen and warm, an inflammatory joint disease such as rheumatism may be behind it. That should be assessed by a doctor.

Self-check: Do I have osteoarthritis?

This short self-check is not a diagnosis, but it helps you gauge whether your symptoms fit osteoarthritis. The more points apply, the more likely it is.

  • The first steps after getting up or after sitting for a long time hurt, then it gets better.
  • My joint hurts on loading, such as climbing stairs, walking or carrying.
  • In the morning the joint is briefly stiff but loosens up within a few minutes.
  • I feel or hear grinding or crunching in the joint.
  • The joint no longer moves as far as it used to.
  • I am over 50 or had a previous joint injury or heavy strain.
What the check means If several points apply, osteoarthritis is likely. Only a medical examination can confirm it. Seek advice promptly if the symptoms limit you in everyday life or get worse quickly.

Which joints are affected?

Osteoarthritis can affect almost any joint, but some particularly often. The affected joint also shapes which symptoms stand out and which treatment helps most.

Knee Knee osteoarthritis (gonarthrosis)

The most common form. Typical are pain when climbing stairs, walking downhill and getting up from a squat. Particularly effective here are strengthening the thigh muscles and, if there is excess weight, weight loss. More on this: Knee pain.

Hip Hip osteoarthritis (coxarthrosis)

The pain often sits in the groin or thigh and can radiate to the knee. An early sign is that the leg turns inward less easily. Exercise therapy and gentle endurance activities help to keep mobility.

Hand Hand osteoarthritis

Often the finger end and middle joints are affected, as well as the base of the thumb. Bony thickening can develop. Local pain gels, hand exercises and, if needed, splints help most here.

The spine is also frequently affected when the small facet joints wear down. This can lead to back and neck pain.

Diagnosis: How is it determined?

The doctor usually makes the diagnosis from the typical symptoms, a physical examination and an X-ray. The X-ray shows signs such as a narrowed joint space, bony outgrowths (osteophytes) and denser bone beneath the cartilage.

An important point: the extent on the X-ray and the level of symptoms do not always match. Blood tests are not part of the osteoarthritis diagnosis itself, but they help rule out other causes such as rheumatoid arthritis or gout.

Treatment overview

Osteoarthritis cannot be cured, but it can be treated well. The goals are to relieve pain, keep mobility and slow the progression. Treatment follows a stepwise approach and always begins with the basics:

  • exercise and targeted training.
  • weight loss if there is excess weight.
  • painkillers as needed, from gel to tablet.
  • aids such as insoles, braces or walking sticks.
  • only when this is not enough, surgery.

Which elements come first depends on the affected joint, the stage and your personal risks.

Medication: the steps of pain therapy

For medication, the rule is: as targeted and as low a dose as possible. Rather than reaching for a tablet straight away, it is best to go step by step.

Step What When it makes sense Good to know
1 Topical NSAIDs as a gel (e.g. diclofenac, ibuprofen) First choice for knee and hand osteoarthritis Only a little active ingredient enters the body, so usually well tolerated
2 Oral NSAIDs as tablets (e.g. ibuprofen, naproxen, diclofenac) For stronger pain or several joints Lowest effective dose, shortest time; with stomach protection (PPI) if there is a stomach risk
3 Cortisone injection into the joint For acute, severe flare-ups of pain Works for a few weeks, repeat only to a limited extent, not a permanent solution
4 Other options (e.g. duloxetine, capsaicin cream) For chronic pain or when NSAIDs are not an option Reserve options that are weighed up individually

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Diclofenac (as a gel or tablet)
As a gel: often the first choice for knee and hand osteoarthritis, because only a little enters the body. As a tablet: more effective, but with a higher risk for the stomach and cardiovascular system. Details: Diclofenac.
Naproxen (tablet)
What: an NSAID with a comparatively more favourable cardiovascular profile, which is why it is often preferred when there is such a risk. Like all NSAIDs: lowest dose, shortest time, with stomach protection if there is a stomach risk. Details: Naproxen.
Do not take NSAIDs long term on your own Anti-inflammatory painkillers (NSAIDs) work well, but with longer use they can strain the stomach, kidneys and cardiovascular system. Take them for as short a time and at as low a dose as possible, and always discuss long-term use with your doctor.

What does little

Some well-known remedies are often used even though their benefit in osteoarthritis is small or unproven:

  • Paracetamol on its own: barely effective in osteoarthritis, at most a short-term add-on.
  • Glucosamine and chondroitin: no convincing proof of effect, not recommended by guidelines.
  • Opioids: only in rare exceptions and with clear risks.
  • Hyaluronic acid injections: the benefit is disputed, and they are usually not recommended.

Exercise and physiotherapy

With osteoarthritis, exercise is not only allowed but one of the most effective measures of all. What matters is that it is the right kind of exercise. Blanket advice like just walk more falls short. What counts:

  • strength training of the surrounding muscles stabilises the joint. With knee osteoarthritis, the thigh muscles (quadriceps) are especially important.
  • gentle endurance activities such as cycling, swimming or water aerobics keep the joint moving without jarring it.
  • physiotherapy helps you learn the right exercises and correct faulty loading.

The combination of exercise and weight loss is particularly effective. Just 5 to 10 percent less body weight can clearly reduce knee pain, because with every step a multiple of your body weight presses on the joint.

Medication plan

NSAIDs, gel or injection: stay on top of it.

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When nothing else helps: a joint replacement

When the conservative measures are exhausted and the pain severely limits quality of life, an artificial joint (joint replacement) can make sense, especially for the knee and hip. The operation replaces the worn joint surfaces, often clearly relieves pain and improves mobility.

A joint arthroscopy with cartilage smoothing, on the other hand, is not recommended for pure knee osteoarthritis, because it has no proven benefit.

When to see a doctor

A doctor's visit makes sense when the symptoms limit you. You do not have to wait until nothing works anymore. You should seek medical advice in the following situations:

  • The pain affects your everyday life or your sleep.
  • The joint gets worse despite treatment.
  • You want to take painkillers for longer and need advice on this.
Get it checked straight away A joint that suddenly swells up, is red and warm, possibly together with a fever, is not normal osteoarthritis. It could be a joint infection or an acute gout attack. A joint that suddenly locks or catches should also be examined quickly. Do not wait.

Stay on top of your osteoarthritis treatment with brite

Whether pain gel, tablets or injection appointments: brite helps you keep track of your medication and symptoms.

  • Intake reminders: never miss your gel or tablet, every day at the right time.
  • Symptom diary: track pain and mobility and see what works.
  • Interaction check: see at a glance whether your medications work well together.
  • Medication plan: always up to date and ready for your next appointment.
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Frequently asked questions

No, lost cartilage cannot regrow. The good news: the symptoms can often be treated well, and with exercise, weight loss and the right therapy you can slow the progression.

Osteoarthritis is wear of the joint cartilage. Arthritis refers to inflammation in the joint, for example rheumatoid arthritis. The two can occur together: an inflamed, irritated osteoarthritis is called activated osteoarthritis.

For knee and hand, topical NSAIDs as a gel are the first choice. If that is not enough, NSAIDs as tablets (for example ibuprofen, naproxen or diclofenac) at a low dose and for a short time are an option. Paracetamol on its own barely helps in osteoarthritis.

Targeted exercise helps. It strengthens the muscles around the joint, keeps it mobile and supplies the cartilage with nutrients. What matters is choosing gentle activities such as cycling, swimming or targeted strength training.

For these supplements there is no convincing proof of effect. The current guidelines do not recommend them for treating osteoarthritis.

A joint replacement is an option when the conservative measures are exhausted and the pain and reduced mobility severely affect quality of life. This most often involves the knee and hip.

The knee (gonarthrosis), hip (coxarthrosis) and hands are particularly often affected. The small joints of the spine can wear down too.

A normal body weight, regular gentle exercise and strong muscles help. Joint injuries should be treated well and one-sided overloading avoided.

Related topics

Quellen

  1. DGOOC: S2k-Leitlinie „Gonarthrose“ (AWMF-Registernummer 033-004), Stand 2018. register.awmf.org/de/leitlinien/detail/033-004
  2. NICE: Osteoarthritis in over 16s, diagnosis and management (NG226), 2022. nice.org.uk/guidance/ng226
  3. IQWiG / gesundheitsinformation.de: Informationen zu Arthrose und Kniearthrose. gesundheitsinformation.de
  4. EULAR und OARSI: Empfehlungen zum Management der Hand-, Hüft- und Kniearthrose.
  5. Deutsche Rheuma-Liga: Patienteninformationen zu Arthrose. rheuma-liga.de
Important note: This article is for general information and does not replace medical advice, diagnosis or treatment. Which osteoarthritis treatment is right for you depends on your individual situation and should be discussed with a doctor. Last updated: June 2026.