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When swallowing hurts or food gets stuck: difficulty swallowing is one of the most common symptoms of all. Sometimes only a harmless sore throat lies behind it, sometimes chronic reflux, an enlarged thyroid – or, more rarely, a serious illness. Here you learn how to tell pain on swallowing (odynophagia) and difficult swallowing (dysphagia) apart, which warning signs you must not ignore and what really helps.
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Difficulty swallowing with shortness of breath, drooling or swelling at the neck? Call emergency number 112 immediately (in the US: 911)!
Difficulty swallowing covers two different phenomena: pain on swallowing (odynophagia) and difficult or obstructed swallowing (dysphagia). The two often occur together but can also occur in isolation – their significance and diagnostics differ.
Acute difficulty swallowing, for example with tonsillitis or reflux oesophagitis, is very common and mostly harmless. Persistent or progressive symptoms – especially in adults with risk factors like smoking, alcohol or ongoing reflux – should be investigated consistently. They can be a sign of a serious illness like oesophageal cancer.
Acute pharyngitis (sore throat): the most common cause of acute pain on swallowing – usually viral. Accompanied by a sore throat, redness, mild fever.
Tonsillitis: severe pain on swallowing, swollen tonsils with whitish coatings, a high fever. With a probably bacterial cause (streptococci), consider antibiotics.
Peritonsillar abscess: one-sided severe pain on swallowing, a pronounced feeling of illness, a muffled voice, trismus. An emergency – drainage necessary.
Glandular fever (infectious mononucleosis): severe throat pain with difficulty swallowing, swollen lymph nodes, tiredness – typical in adolescents and young adults.
Fungal infection (thrush): white coatings in the mouth and throat, pain on swallowing – especially in immunosuppressed people, with inhaled steroids, antibiotic use or diabetes.
Epiglottitis: inflammation of the epiglottis with shortness of breath, a high fever, drooling. An emergency – especially in children.
Reflux oesophagitis: the most common cause of chronic difficulty swallowing in adults. Burning behind the breastbone, heartburn, pain on swallowing.
Eosinophilic oesophagitis: a chronic inflammatory disease of the oesophagus, often associated with allergies. The typical symptom: the feeling that solids (bread, meat) get stuck.
Achalasia and other motility disorders: disturbed movement of the oesophagus – dysphagia for solids and liquids, regurgitation, chest pain.
Strictures (narrowings): from chronic reflux, earlier chemical burns or tumour diseases.
Oesophageal diverticulum: outpouchings of the oesophagus, can cause dysphagia and bad breath.
Oesophageal cancer: progressive dysphagia, at first for solid foods, then for liquids too. Risk factors: chronic reflux (Barrett's oesophagus), smoking, alcohol, older age.
Enlarged thyroid (goitre): large nodules or goitres can exert pressure on the oesophagus and windpipe – difficulty swallowing, a globus sensation, hoarseness from pressure on the nerve to the vocal cords. More: thyroid nodules.
Thyroid cancer: rare, but important to rule out. Accompanying symptoms: one-sided swelling at the neck, hoarseness, rapidly growing nodules, enlarged lymph nodes.
Tumours of the mouth, throat, larynx: especially in smokers and people with alcohol consumption. Persistent hoarseness, one-sided throat pain, difficulty swallowing, bloody sputum, swollen lymph nodes.
Lymphomas: can affect the neck lymph nodes or tonsils – difficulty swallowing, often with B symptoms (night sweats, fever, weight loss).
Stroke: a common cause of acute oropharyngeal dysphagia. An important complication: aspiration with pneumonia.
Parkinson's, multiple sclerosis, ALS: chronic neurodegenerative diseases with increasing dysphagia.
Dementia: swallowing disorders are common in the course – a risk of aspiration. Special food and swallowing training can help.
Myasthenia gravis: exertion-dependent muscle weakness, including of the swallowing muscles.
With difficulty swallowing, the most important diagnostic question is whether it hurts or whether it gets stuck – the two phenomena have different typical causes and lead to different diagnostics.
| Feature | Odynophagia (pain) | Dysphagia (sticking) |
|---|---|---|
| Main symptom | Pain on swallowing | The feeling that food does not slip through |
| Typical causes | Pharyngitis, tonsillitis, reflux oesophagitis, thrush | Achalasia, strictures, eosinophilic oesophagitis, neurological |
| Common course | Acute, often viral, subsides on its own | Chronic, often progressive |
| Most important diagnostics | Inspection, a rapid strep test if needed | Gastroscopy, manometry if needed |
Also important: the globus sensation (globus pharyngeus) – the feeling of a lump in the throat without anything actually getting stuck. Often stress- or reflux-related, usually not a sign of a serious illness. With persistence or accompanying symptoms (hoarseness, weight loss) it should nonetheless be investigated.
Viral pharyngitis: symptomatic – lozenges, sage tea, painkillers. Antibiotics are not necessary.
Bacterial tonsillitis: with a suspicion of streptococci, an antibiotic if needed.
Reflux oesophagitis: proton pump inhibitors (PPIs), lifestyle changes – small meals, eating nothing late in the evening, raising the upper body.
Eosinophilic oesophagitis: PPIs, topical steroids, an elimination diet with allergies.
Achalasia: endoscopic or surgical procedures (POEM, Heller myotomy).
Strictures: endoscopic dilation (widening).
Tumours: an individual oncological concept (surgery, chemotherapy, radiotherapy).
Neurological dysphagia: speech-therapy swallowing training, adjusting the consistency of food, PEG feeding if needed.
With an acute sore throat, warm tea, lozenges, drinking enough and resting the voice help. With reflux: small meals, eating nothing 2–3 hours before going to bed, raising the upper body. Reduce coffee, alcohol, fatty and spicy foods. Stop smoking – this is the most important step not only for reflux but also for cancer prevention.
Some medications can damage the oesophagus directly if they are not transported down sufficiently – so-called tablet-induced oesophagitis. Others promote fungal infections or treat the cause. An overview:
| Medication | Effect on swallowing |
|---|---|
| Bisphosphonates (e.g. alendronate) | Can damage the lining of the oesophagus directly – take upright, do not lie down for 30 min afterwards |
| Doxycycline / tetracyclines | Tablet-induced oesophagitis possible – always take with plenty of water |
| Inhaled corticosteroids (asthma/COPD sprays) | Promote fungal infections (thrush) in the mouth/throat – rinse the mouth after use |
| Proton pump inhibitors (omeprazole, pantoprazole) | Treat reflux-related difficulty swallowing – effect after days to weeks |
Also ferrous sulphate, NSAIDs and potassium chloride can attack the lining of the oesophagus. The most important protective measure: take upright, with plenty of water, and do not lie down for at least 30 minutes.
Digital medication plan: record all preparations – your GP, ENT, gastroenterology and endocrinology see immediately which active ingredients can irritate the oesophagus. → Create a medication plan
Interaction check: which medications can irritate the oesophagus? → Start the interaction check
Intake reminder: take antibiotics, PPIs, painkillers or thyroid medications on time. → Set up a reminder
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