Mood swings: causes, help and when to see a doctor

Relaxed in the morning, irritable at midday, sad for no reason in the evening: almost everyone knows mood swings. To a certain degree they are part of life. They become a burden when they occur frequently, intensely or without a recognisable trigger and affect relationships, work or sleep. Behind pronounced swings there is often a treatable cause – the thyroid, the cycle or the menopause, but sometimes also depression or bipolar disorder. Here you learn when mood swings are normal, when they should be investigated medically – and where to get immediate help in a crisis.

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Table of contents

  1. What you can do now
  2. What happens in the body?
  3. Common causes
  4. Normal or abnormal?
  5. What really helps
  6. Is it your medication?
  7. Warning signs: when to see a doctor?
  8. Preparing for the doctor's appointment
  9. How brite supports you
  10. FAQ
Note With suicidal thoughts or an acute crisis, get help immediately: Telefonseelsorge (German crisis line) 0800 111 0 111 or 0800 111 0 222 – free, around the clock. In the US: call or text 988 (Suicide & Crisis Lifeline).

1. What you can do now

First steps with mood swings

  • Keep a mood diary: over 2–3 weeks, document mood, sleep, cycle and triggers – this helps to recognise patterns.
  • Have hormonal causes checked: thyroid (TSH), cycle connection – common and treatable causes.
  • Stabilise sleep: regular times, a screen break before going to bed. Lack of sleep considerably intensifies swings.
  • Exercise and daylight: regular exercise and daylight have a measurable mood-stabilising effect.
  • Check medications: cortisone, beta blockers, hormonal contraception can influence mood – discuss with your practice.
EMERGENCY: get help immediately With suicidal thoughts, thoughts of self-harm or hopelessness – contact one of the following points of contact immediately:
Telefonseelsorge (German crisis line): 0800 111 0 111 or 0800 111 0 222 (free, around the clock). In the US: call or text 988 (Suicide & Crisis Lifeline).
On-call medical service (in Germany): 116 117 (also at night and at the weekend).
In acute danger to life: emergency number 112 (in the US: 911) or the nearest emergency department.
Also with phases of excessive drive, grandiose ideas and a clearly reduced need for sleep (suspicion of mania / bipolar disorder), seek medical help promptly.

2. Understanding mood swings – what happens in the body?

Mood swings describe a frequent, often rapid change in emotional state. Within hours or days, the mood switches between positive feelings like joy and balance and negative feelings like irritability, sadness, anger or inner restlessness. To a certain degree, such changes are completely normal and part of human experience.

Mood swings become problematic when they occur frequently, intensely or without a recognisable trigger and noticeably affect life – relationships, work, sleep or one's own wellbeing. Then there is often a medical, hormonal or psychological cause behind it that should be investigated.

Hormonal swings are the most common trigger

Thyroid: an overactive thyroid causes irritability, inner restlessness and nervousness, an underactive one rather a low mood and a lack of drive. Both can be treated well – a TSH value clarifies it quickly.

Cycle and PMS: 3–8 days before menstruation, many women report low moods, irritability or anxiousness. With strongly pronounced symptoms it is called premenstrual dysphoric disorder (PMDD) – treatable.

Menopause: the drop in oestrogen can trigger mood swings, sleep problems and depressive moods. Hot flushes and night-time lack of sleep intensify the symptoms.

Pregnancy and the postnatal period: hormonal changes alter the mood in both directions. Postnatal depression should be recognised and treated in time.

In men – testosterone: a testosterone deficiency in middle to older age can show itself as irritability, a lack of drive and mood swings – in men often hidden behind "tiredness" or "stress".

Important: mood swings in men look different Instead of sadness, in men irritability, aggressiveness, social withdrawal or increased alcohol consumption often dominate. This "male depression" is frequently overlooked. If you as a man or as a relative notice such changes – a medical assessment is sensible, even if the word "depression" does not seem fitting at first.

3. Common causes of mood swings

3.1 Hormonal

Overactive thyroid and underactive thyroid, premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD), menopause, pregnancy and the postnatal period, testosterone deficiency.

3.2 Psychological

Depression: a low mood over a longer period, a lack of drive, loss of interest, sleep problems, self-reproach.

Bipolar disorder: a change between depressive and manic/hypomanic phases (elevated drive, reduced need for sleep, increased activity, risky behaviour).

Cyclothymia: a persistently unstable mood with numerous mild depressive and hypomanic phases.

Borderline personality disorder: rapid, intense mood changes, often as a reaction to relationship events.

Anxiety disorders and adjustment disorders: can be accompanied by pronounced mood swings.

3.3 Lifestyle and environment

Lack of sleep, stress, being over- or under-challenged, lonely phases of life, acute strains (separation, bereavement, job loss), vitamin D deficiency in winter, substance use (alcohol, cannabis, drugs).

3.4 Medications

Cortisone, beta blockers, thyroid preparations, hormonal contraception, antidepressants (especially at the start), sleeping pills, some painkillers.

3.5 Physical illnesses

Vitamin D or B12 deficiency, chronic illnesses (diabetes, heart failure), neurological illnesses (Parkinson's, multiple sclerosis, dementia), chronic pain.

4. Normal or abnormal?

Mood changes are not automatically abnormal – everyone has them. The transition from "normal" to "needs investigation" shows itself in a few features:

FeatureNormal swingsAbnormal swings
TriggerRecognisable (stress, sleep, conflict)Often without a recognisable trigger
IntensityProportionate to the situationDisproportionate or overwhelming
DurationHours to a few daysWeeks to months
Everyday lifeRemains functionalWork, relationships, sleep are affected
Accompanying symptomsNoneSleep problems, loss of energy, suicidal thoughts, physical symptoms
Table scrollable to the right

Also important: in adolescents, mood swings during puberty are largely normal – hormonal change, finding an identity, social pressure and shifts in sleep come together. Attention is warranted, however, when persistent dejection, social withdrawal, a drop in school performance, self-harm or suicidal thoughts are added. Point of contact: the paediatric practice, school psychology services or the Nummer gegen Kummer (German youth helpline): 116 111.

5. What really helps

For hormonal causes

Overactive thyroid → antithyroid drugs; underactive thyroid → levothyroxine. For PMS/PMDD: lifestyle adjustment, if needed an SSRI in the luteal phase, in some cases hormonal contraception. For menopausal symptoms: hormone replacement therapy after an individual assessment. For testosterone deficiency in men: substitution after a confirmed diagnosis.

For psychological causes

Psychotherapy (cognitive behavioural therapy, psychodynamic therapy) is the first-line therapy for depression, anxiety disorder and personality disorders. For moderate to severe episodes, a combination with drug therapy (SSRIs, SNRIs, mood stabilizers for bipolar disorder such as lithium, valproate, lamotrigine). Important: the diagnosis of bipolar disorder must be clarified before antidepressant therapy – antidepressants without a mood stabilizer can trigger manic phases in bipolar patients.

Self-help and everyday life

A regular sleep-wake rhythm, exercise in the fresh air, a balanced diet, maintaining social contacts, reducing alcohol and caffeine. A mood diary via apps or notebooks helps to recognise triggers and to document treatment success. With mild low moods, St John's wort, lavender, passionflower or valerian can have a supporting effect – caution: St John's wort has numerous interactions (e.g. with the pill and blood thinners), get medical advice before taking it.

6. Is it your medication?

Some medications can change the mood – others are the most important treatment option. An overview:

MedicationEffect on mood
Cortisone (systemic)Can trigger irritability, sleep problems, euphoria or depressive moods – especially at higher doses
Hormonal contraceptionCan intensify low moods in some women – a change of preparation can help
SSRIs / SNRIs (antidepressants)First-line therapy for depression – the effect sets in after 2–6 weeks, possibly restlessness at first
Mood stabilizers (lithium, valproate, lamotrigine)Core therapy for bipolar disorder – regular blood level checks necessary
Table scrollable to the right

Also beta blockers, thyroid preparations (with over- or under-dosing), sleeping pills and some painkillers can influence mood. If mood swings coincide in time with a new medication, this should be discussed medically.

Important: never stop on your own Antidepressants and mood stabilizers must not be stopped suddenly – this can trigger discontinuation symptoms or a relapse. Hormonal contraception and thyroid medications should also only be paused in agreement with your practice. Check your medication in the interaction check.

Digital medication plan: record all preparations – your GP, psychiatry, endocrinology and gynaecology see immediately which active ingredients can influence the mood. → Create a medication plan

Interaction check: which medications can change the mood? → Start the interaction check

Intake reminder: take antidepressants, mood stabilizers and thyroid medications regularly. → Set up a reminder

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7. When should you have mood swings investigated?

  • Immediate help: suicidal thoughts, thoughts of self-harm or hopelessness – Telefonseelsorge (German crisis line) 0800 111 0 111 / 0800 111 0 222 (in the US: 988) or the emergency department.
  • See a doctor immediately: phases of excessive drive, grandiose ideas, a clearly reduced need for sleep – suspicion of mania / bipolar disorder.
  • See a doctor promptly: a persistent depressive mood for more than two weeks.
  • See a doctor promptly: a clear impairment of work, relationships or everyday life.
  • See a doctor promptly: mood swings with physical symptoms (weight loss, a racing heart, hot flushes) – a thyroid assessment is sensible.
  • See a doctor promptly: strongly pronounced cycle-dependent symptoms – suspicion of PMDD, treatable.
  • In adolescents: persistent dejection, social withdrawal, a drop in performance, self-harm – Nummer gegen Kummer (German youth helpline) 116 111 or the paediatric practice.
  • In men: persistent irritability, social withdrawal, increased alcohol consumption – this too can be an expression of depression.

8. Preparing for the doctor's appointment – your checklist

  • Since when? Weeks, months, always? A concrete start?
  • How often? Daily, weekly, cycle-dependent?
  • Trigger? Recognisable triggers or without a cause?
  • Accompanying symptoms: sleep problems, loss of energy, a change in appetite, physical symptoms (a racing heart, hot flushes, weight loss)?
  • Mood diary: over 2–3 weeks, document mood, sleep, cycle, triggers – very helpful for the practice.
  • Medications: a complete list – especially cortisone, hormonal contraception, thyroid preparations.
  • Family: depression, bipolar disorder, suicides in the family?

More on this: Preparing for a doctor's appointment.

How brite supports you with mood swings

brite helps you to organise your therapy and medication reliably – so that antidepressants or mood stabilizers work consistently and no appointment or blood level check is forgotten.

  • Intake reminder – take antidepressants, mood stabilizers or thyroid medications on time: brite reminds you reliably. Set up a reminder
  • Interaction check – which medications can change the mood? Check interactions for free. Check now
  • Digital medication plan – all medications clearly laid out for your GP, psychiatry, endocrinology and gynaecology. To the medication plan
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