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You wake up in the middle of the night, the pillow is wet, the T-shirt soaked through – and that despite the heating not running at full blast. Night sweats are not just unpleasant but can be a signal from your body that something is wrong. The causes range from harmless factors such as a bedroom that is too warm to medication side effects or conditions that require treatment. Here you will learn how to interpret your night sweats, which medications come into question as triggers and when you should see a doctor.
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With night sweats accompanied by unexplained weight loss, fever or swollen lymph nodes, have it assessed by a doctor promptly.
Sweating at night is not automatically night sweats in the medical sense. If you wake up only slightly damp because the duvet is too warm, that is normal. It becomes medically relevant when you regularly sweat so much that you have to change your nightwear and the bedding – despite an appropriate sleeping temperature.
Doctors distinguish three degrees of severity:
| Degree | Description | Action needed |
|---|---|---|
| Degree 1 | Light sweating on the head and trunk – clothing damp, no change needed | Observe |
| Degree 2 | Clothing soaked through, a change of bedding needed | Have the cause assessed |
| Degree 3 | Complete soaking – pyjamas, sheet, sometimes the mattress affected | See a doctor promptly |
From degree 2 onwards, you should have the cause assessed by a doctor – especially if it happens regularly.
Many active ingredients can cause night sweats as a side effect. According to one study, 5–14 % of people who take antidepressants suffer from nocturnal hyperhidrosis. Particularly affected are:
| Medication | Mechanism |
|---|---|
| Citalopram, Escitalopram (antidepressants) | The most common SSRI side effect – affects 5–14 % of users |
| Prednisolone (corticosteroid) | Boosts the metabolism and can trigger sweating |
| Metformin | With night-time hypoglycaemia – often with palpitations and trembling |
| Paracetamol, Ibuprofen | Sweating fits as the fever-reducing effect wears off |
| Semaglutide (Ozempic/Wegovy) | Night sweats as a known side effect |
The menopause (perimenopause) is the best-known hormonal cause of night sweats – up to 75 % of women are affected. Falling oestrogen levels throw the temperature regulation centre in the hypothalamus into confusion: the body "believes" it is overheated and reacts with sweating. An overactive thyroid, hormonal fluctuations in the cycle or an overdose of levothyroxine can also cause night sweats.
Colds, flu and other feverish infections often trigger night-time sweating – this kind of night sweats usually disappears after 3–7 days. Chronic infections (e.g. tuberculosis, HIV) and bacterial inflammation of the inner lining of the heart (endocarditis) can also cause night sweats.
Psychological stress activates the sympathetic nervous system. The body reacts with sweating, palpitations and restlessness even in sleep. Chronic stress can lead to persistent night-time sweating.
Alcohol widens the blood vessels and disturbs temperature regulation. Spicy food can have the same effect. Heavy alcohol consumption in the evening is one of the most common harmless causes of night sweats.
Cool the bedroom to 16–18 °C, use breathable bedding made of cotton or linen, avoid synthetic duvets and pillows. Keep a second set of bedding within reach so that you can change quickly with heavy sweating.
No alcohol, no spicy food, no heavy meals in the evening. Avoid caffeine after 2 pm. A short relaxation exercise before sleeping (progressive muscle relaxation or the 4-7-8 breathing technique) can reduce stress-related sweating.
Sage tea (2–3 cups a day) is considered a traditional remedy against excessive sweating – sage leaves contain essential oils that inhibit the sweat glands. Lavender oil on the pillow can have a calming effect and promote falling and staying asleep.
Never stop medications on your own. Speak to your doctor – often a change of the intake time helps (e.g. prednisolone in the morning instead of the evening), a dose adjustment or a switch to an alternative preparation.
If the night sweats began at the same time as a new prescription or a dose increase, you should check your medication.
Digital medication plan: record all preparations and recognise whether the night sweats correlate with a medication change. → Create a medication plan
Interaction check: find out whether your combination intensifies the sweating. → Start the interaction check
Intake reminder: a stable intake prevents rebound effects (e.g. blood sugar fluctuations with metformin). → Set up a reminder
Register for free nowOccasional sweating at night is mostly harmless. See a doctor if:
So that your doctor finds the cause quickly, prepare this information:
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