PTSD:
trauma therapy first, medication as a support

At a glance

What it isA treatable reaction to an exceptionally distressing event — not a weakness of character
Four symptom clustersRe-experiencing, avoidance, negative changes in thinking and mood, hyperarousal
Treatment of choiceTrauma-focused psychotherapy, such as EMDR or cognitive processing therapy
MedicationA support, not a substitute: certain antidepressants. Benzodiazepines are not recommended
Guideline & ICD-10German S3 guideline on post-traumatic stress disorder (AWMF 155-001) · F43.1

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1. What is post-traumatic stress disorder?

Post-traumatic stress disorder (PTSD) is one possible reaction to an event of exceptional threat — a serious accident, physical or sexual violence, war and displacement, a natural disaster, or witnessing such an event as a relative or as an emergency worker.¹

The most important sentence first: PTSD is a treatable condition, not a weakness. It does not arise because someone is not resilient enough, but because an experience overwhelmed the normal way of processing things. The memory is then stored in fragments — it does not feel like the past, but like a present that can break in again at any moment.

Some reassurance that matters. After a distressing event almost everyone reacts with jumpiness, sleep problems and intrusive memories — a normal reaction to an abnormal situation, which in most people settles by itself over the first few weeks. Only when the symptoms stay is it called PTSD.

From the outside this is hard to follow, and that is exactly what makes it lonely. Many describe “functioning” while an alarm runs constantly inside. Others feel ashamed because they think the event was “not bad enough”. Both are common — and a reason to get support.


2. The four symptom clusters

The symptoms fall into four groups. They almost never appear on their own, and their intensity can swing from week to week.¹,²

Re-experiencing (intrusions)

Intrusive images, nightmares and flashbacks — moments in which what happened feels as though it were happening again right now. They are often set off by harmless cues: a sound, a smell, a tone of voice. Not understanding the trigger yourself is typical and is no sign that you are imagining things.

Avoidance

Places, conversations, people or thoughts that are reminders of the event get avoided. In the short term that brings relief; in the long term everyday life narrows — and the memory never gets the chance to settle into place. That is why avoidance is a central starting point in therapy.

Negative changes in thinking and mood

Persistent guilt and shame (“I should have done something”), deep mistrust, loss of interest, emotional numbness, estrangement from the people closest to you, and gaps in memory. This group is the one most often overlooked from the outside, because it is quiet.

Hyperarousal

Constant watchfulness, marked jumpiness, irritability, concentration problems, inner restlessness and sleep disorders. Physically this often shows up as a racing heart, sweating or tension: the body stays on alert even when there is no danger.


3. The timeline: acute reaction, PTSD, delayed onset

How much time has passed since the event is decisive for making sense of it — and it explains why treatment straight after a trauma is not the same as treatment for a long-standing condition.

  • Acute stress reaction (hours to days): numbness, a sense of unreality, jumpiness, sleeplessness — a normal stress response that usually settles quickly. What helps here is safety, rest and reliable people.
  • Up to about four weeks: if the symptoms persist and restrict everyday life, a professional assessment makes sense.
  • PTSD (from about four weeks): if the symptoms carry on for longer than roughly a month, it is called PTSD. It responds well to treatment.
  • Delayed onset: the symptoms can appear only months or years later, often triggered by a new strain or by retirement — that makes the connection no less real.
  • Complex PTSD: after prolonged or repeated traumatisation, problems with emotional regulation, self-image and relationships are added; treatment then takes longer.

4. Who develops it — and why not everyone does

Whether PTSD follows a trauma depends on several factors. None of them is a question of blame:¹,³

  • The kind of event — deliberate violence caused by people leaves PTSD behind more often than accidents or natural disasters.
  • Duration and repetition — one-off events are on average processed better than prolonged traumatisation.
  • Closeness and loss of control — being in danger of your life yourself and the feeling of being completely at another's mercy raise the risk.
  • What happens afterwards — social support is one of the strongest protective factors; isolation and blame work in the other direction.
  • Earlier burdens — previous traumatisation as well as an existing depression or anxiety disorder; and ambulance work, policing and nursing all bring repeated contact with distressing events.
The medication angle. Medicines do not cause PTSD, but they can change the picture: sedatives and alcohol dampen the tension in the short term and make processing harder in the long term. And restlessness, palpitations or sleeplessness can also be a side effect. That is why the complete medication list belongs in every first appointment.

5. Diagnosis: how it is made

The diagnosis is made by a psychotherapist or a psychiatrist in conversation — not by a test on the internet and not by a laboratory value.

  • A detailed conversation: which symptoms, since when, how restricting? You do not have to tell everything — for the diagnosis it is usually enough that the event is named.
  • Structured questionnaires: they capture the symptom clusters and the severity and make the course measurable.
  • Co-occurring conditions: depression, anxiety disorder, substance use and sleep disorders are recorded as well, because they shape the treatment.
  • Physical work-up: thyroid values, a blood count and your current medication, so that physical causes of restlessness and exhaustion are not missed.
  • Safety check: are there suicidal thoughts, or is there still contact with a dangerous situation? That is what determines the urgency.

A common misunderstanding: for the diagnosis the memory does not have to be complete — gaps in memory are actually part of the picture. Nor is any proof needed that the event was “bad enough”. What counts is how it was experienced.

6. Treatment: trauma-focused psychotherapy first

Here is the central message, and it runs against a widespread expectation: the guidelines recommend trauma-focused psychotherapy as first-line treatment — not a medicine.¹ A tablet can support sleep and mood, but it does not put the traumatic memory in its place. That is exactly what psychotherapy does.

“Trauma-focused” means the experience is worked through deliberately instead of being skirted around. That sounds frightening at first — which is why good trauma therapy is built up in stages.

So it begins with safety and stabilisation: as long as a threat continues, ending it comes before any trauma work. Added to that is psychoeducation — understanding why the body sounds the alarm takes much of the force out of the fear of your own symptoms — and techniques for anchoring yourself in the present during flashbacks.

First line Trauma-focused approaches
EMDR
The distressing memory is called up briefly while attention is directed to an alternating stimulus, usually guided eye movements. The aim is for the memory to lose its quality of being present.
Cognitive processing therapy
Works on the beliefs that have taken hold since the trauma — guilt, shame, “the world is never safe”. These statements are examined systematically and corrected.
Behavioural therapy with exposure
The event is gone through in a protected setting until the memory loses its threat.
What you are entitled to expect. Good trauma therapy does not steamroll you: you have a say in what is discussed and when, and you may stop at any time.

7. Medication: what supports, what harms

Medicines have a clearly defined place in PTSD: they can improve sleep, mood and tension and so create the strength for therapy. They do not dissolve the traumatic memory. The choice and the dose are always set by the treating practice.

Drug classRole in PTSDOnset of effectHow to read it
SSRIs (e.g. sertraline)The best-studied additionOver several weeksA support alongside psychotherapy, not a substitute for it. Restlessness can increase at the start
SNRIs (e.g. venlafaxine)An alternative where there is no response or no toleranceOver several weeksBlood pressure checks are sensible; do not stop abruptly
Benzodiazepines (e.g. lorazepam)Expressly not recommended in PTSDMinutesRapid tolerance and dependence, dampening of emotional processing
Sleeping tablets in generalAt most short term and with good reasonShort termLoss of effect and risk of dependence; behavioural approaches are better
Table scrolls to the right

The best studied are the serotonin reuptake inhibitors; sertraline is the preparation used most often, and venlafaxine is a possible alternative. Important for your expectations: the effect does not set in straight away but over several weeks, and inner restlessness may increase at first — a known pattern, not a sign that the medicine is wrong for you.

Do not stop abruptly. Stopping antidepressants suddenly can bring on dizziness, odd sensations and irritability, which are easily mistaken for a relapse — see Stopping SSRIs.
Sedatives: brief relief, long-term harm. Benzodiazepines such as lorazepam dampen anxiety within minutes — and that is exactly what makes them a problem in PTSD. The guidelines do not recommend them: they lead quickly to tolerance and dependence and dampen the emotional processing that trauma therapy needs. If you are already taking such a medicine: do not stop it on your own — an abrupt end can be dangerous. Agree the tapering with your practice, see Stopping medications.

Alcohol, too, works like an instant sedative: it worsens sleep, intensifies nightmares and raises the risk of dependence — combined with medicines, further risks are added, see Medications and alcohol. Drinking regularly to get through the evening is a symptom that belongs in the treatment.

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8. Nightmares and sleep

Sleep is affected almost every time — and at the same time it is one of the most effective places to start, because with better sleep all the other symptoms are easier to bear. Two patterns dominate: not being able to fall asleep, and waking from recurring nightmares.

Nightmares after a trauma are not a side issue but a complaint in their own right that can be treated specifically. Behavioural approaches work on deliberately rewriting the dream and rehearsing the new version while awake; for some of those affected this changes the burden at night considerably. In individual cases medication support is added — a decision for a specialist.

What helps day to day: fixed sleeping times, no alcohol as a sleep aid, getting up briefly at night rather than brooding — and writing your sleep down, because otherwise changes go unnoticed. The basics are under Sleep disorders.

Take care with sleeping tablets. They work quickly, but often lose their effect just as quickly and can cause dependence; with benzodiazepines particular restraint applies in PTSD. What realistically helps is set out in Sleeping pills: what really helps.

9. Co-occurring conditions

PTSD rarely comes alone — and an untreated co-occurring condition can make trauma therapy harder.

  • Depression — a lack of drive and hopelessness very often occur alongside it, see Depression.
  • Anxiety and panic disorders — the lasting hyperarousal often turns into generalised anxiety or panic attacks, see Anxiety disorders.
  • Substance use — alcohol and sleeping or sedative tablets often serve to calm things down; this is exactly where the course frequently gets worse.
  • States of exhaustion — the line between this and burnout is blurred; what matters is whether re-experiencing is in the foreground.
  • Physical symptoms — chronic pain and palpitations are common and are often investigated as purely physical for a long time.

10. Bridging the wait: where to turn

One problem should not be glossed over: in many places the wait for a psychotherapy place runs to months — particularly bitter when you have just brought yourself to ask for help. Even so, that time can be bridged.

  • The appointment service (Terminservicestelle) on 116 117: it arranges appointments for the psychotherapy consultation session across Germany — the official way in, and quicker than searching on your own.
  • The psychotherapy consultation session: a first assessment appointment that every practice licensed by the statutory health insurance offers. Acute treatment can follow from it, without a full therapy place having to be free.
  • Trauma outpatient clinics: at many hospitals, some with appointments at short notice. After violent crime the federal states cover the cost of prompt initial care.
  • Your GP practice: for an assessment, a sick note and referrals — it can coordinate things when you do not have the energy for the search.
  • The social psychiatric service and self-help: the service can be reached free of charge and without an appointment at every public health office (Gesundheitsamt), including by relatives; self-help groups work against isolation.
  • Telefonseelsorge, the German emotional support helpline: round the clock, free of charge and anonymous on 0800 111 0 111 and 0800 111 0 222, and also by chat and email.
If you are thinking about suicide, get help immediately. Call the emergency number 112 (emergency services in Germany) or go to the nearest psychiatric hospital — you will be helped there around the clock, even without an appointment. Telefonseelsorge, the German emotional support helpline, can be reached at any time free of charge on 0800 111 0 111 or 0800 111 0 222. Do not stay on your own: tell someone near you. These thoughts are a symptom of the illness and can be treated.
Asking for help is a sign of strength. It takes more courage to phone a practice than to carry on as before. If making the call is hard: write down three sentences beforehand — a structure for that is in Prepare for a doctor's appointment.

11. Everyday life with PTSD

  • Know your triggers, but do not arrange your life around them — recognising triggers helps; avoiding all of them makes everyday life narrower and narrower.
  • Structure and movement — fixed times give the overstimulated system a frame, and moderate exercise lowers the level of tension.
  • Keep a record — note tension, sleep, nightmares and medicines over weeks. That shows up progress that gets lost in how you feel from day to day; strategies in the guide Chronic illness in everyday life.

For the people close to you a single sentence helps: “If I seem absent, I just need a moment of quiet, it is not about you.” And for relatives: stay available without pushing. Questions like “Why can't you get over it?” shift the responsibility onto the person affected; what helps more are concrete offers — coming along to the appointment, making the phone call, taking something off their hands in daily life.

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FAQ: Common questions about PTSD

When the typical symptoms after an exceptionally distressing event last longer than about four weeks and restrict everyday life. In the first days and weeks, by contrast, jumpiness, sleep problems and intrusive memories are a normal reaction that usually settles by itself.
Some of those affected recover without treatment as well, above all where social support is good. If the symptoms persist over months, that becomes less likely. Trauma-focused psychotherapy clearly improves the outlook, even when the event was a long time ago.
No, and certainly not straight away. Trauma therapy begins with stabilisation. When and how far the event is worked on is something you have a say in — and you may say at any time that it is becoming too much.
As a rule not. The guidelines recommend trauma-focused psychotherapy as first-line treatment; medicines count as an addition. They can improve sleep and tension and make therapy possible in the first place, but they do not put the memory in its place.
Benzodiazepines relieve anxiety within minutes, but they lead quickly to tolerance and dependence and dampen the emotional processing that trauma therapy needs. Anyone already taking them should on no account stop on their own, but have the tapering supervised medically.
Through the appointment service on 116 117 you can get an appointment for a psychotherapy consultation session, out of which acute treatment can also follow. Alongside that there are trauma outpatient clinics, the social psychiatric service and Telefonseelsorge, the German emotional support helpline, on 0800 111 0 111.

Sources

  1. German S3 guideline on post-traumatic stress disorder (AWMF reg. no. 155-001) — German source. awmf.org
  2. gesund.bund.de, the national health portal of the German Federal Ministry of Health: PTSD. Accessed 2026 — German source. gesund.bund.de
  3. Gesundheitsinformation.de, German Institute for Quality and Efficiency in Health Care (IQWiG): PTSD. Accessed 2026 — German source. gesundheitsinformation.de
  4. MSD Manual, Consumer Version: PTSD. Accessed 2026. msdmanuals.com

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Medical disclaimer: This article is for general information and does not replace medical or psychotherapeutic advice, diagnosis or treatment. If you are having suicidal thoughts, please call the emergency number 112 straight away or ring Telefonseelsorge, the German emotional support helpline, on 0800 111 0 111. Sedatives and sleeping tablets must not be stopped abruptly; the choice of medicine and its dose is always set individually by the treating practice. Last updated: August 2026.