Anxiety Disorder:
Symptoms, Types and Modern Treatment
At a glance
FrequencyOne of the most common mental health conditions - many adults are affected at some point in their lives
TypesGeneralized anxiety disorder, panic disorder, social anxiety disorder, specific phobias, agoraphobia
TreatableVery treatable - psychotherapy and/or medications markedly improve the symptoms in most of those affected
Treatment of choiceCognitive behavioral therapy (CBT) with exposure - the best-studied form of treatment
MedicationsSSRIs / SNRIs as first line; pregabalin for generalized anxiety; benzodiazepines only short-term
ICD-10F40 (phobic disorders), F41 (other anxiety disorders)
1. What is an anxiety disorder?
Anxiety is a normal and vital feeling. It warns of danger and prepares the body for fight or flight. We only speak of an anxiety disorder when the anxiety occurs disproportionately strongly, frequently, or for a long time, has no real cause, and considerably affects everyday life.1
Anxiety disorders are among the most common mental health conditions of all. Nevertheless, many of those affected only seek help after years - out of shame, because they cannot make sense of the symptoms, or because they believe they simply have to endure the anxiety.1,2
The good news: anxiety disorders are very treatable
Psychotherapy - above all cognitive behavioral therapy (CBT) with exposure - is highly effective and is recommended by the guideline as a first-line treatment. In many of those affected, the symptoms can be markedly improved or completely overcome.1
2. Types
Generalized anxiety disorder (GAD)
Persistent, exaggerated worrying about various areas of life (health, work, family, finances) - on most days over at least six months. The worries cannot be controlled. Often accompanied by muscle tension, restlessness, sleep disorders, and irritability.
Panic disorder
Recurring, unexpected
panic attacks - sudden attacks of intense anxiety with physical symptoms (
a racing heart, shortness of breath, sweating, dizziness, fear of dying). Between the attacks, there is often a fear of the next attack (anticipatory anxiety).
Agoraphobia
Fear of situations from which escape would be difficult or in which no help would be available - public places, crowds, public transport, department stores. Can occur with or without panic disorder and often leads to avoidance behavior.
Social anxiety disorder (social phobia)
Marked fear of social situations in which one might be observed, judged, or embarrassed - e.g. public speaking, eating in front of others, conversations with strangers. Goes beyond normal shyness.
Specific phobias
Intense, disproportionate fear of certain objects or situations - e.g. heights, flying, spiders, injections, blood, enclosed spaces. Usually leads to avoidance.
3. Symptoms
Psychological symptoms
- Intense, disproportionate anxiety or worry
- A feeling of threat with no real cause
- Avoidance behavior - anxiety-triggering situations are avoided, which reinforces the anxiety over the long term
- Difficulty concentrating
- Irritability, inner restlessness
- Catastrophizing - the worst is expected
Physical symptoms
Often the GP, cardiology, or emergency department first
Because of the physical symptoms, many of those affected first go to their GP practice, cardiology, or the emergency department - without knowing that an anxiety disorder is the cause. An open conversation about possible psychological triggers can shorten the path to the right treatment.
4. Causes
Anxiety disorders usually arise through an interplay of several factors.1
- Genetics: a family predisposition plays a role - anxiety disorders occur more frequently in families.
- Neurobiology: changes in the balance of neurotransmitters (above all serotonin, noradrenaline, GABA) and in brain regions that process fear (the amygdala, the prefrontal cortex).
- Learning history: negative experiences, traumatic events, learned avoidance behavior, overprotective upbringing.
- Stress: chronic stress, stressful life events, transitional phases (a job change, separation, loss).
- Comorbidities: anxiety disorders often occur together with depression, ADHD, addictions, or physical illnesses.
5. Diagnosis
- Clinical interview: the basis of the diagnosis. Capturing the symptoms, the duration, the impairment, and the avoidance behavior.
- Standardized questionnaires: e.g. the GAD-7 (generalized anxiety), the PHQ (anxiety and depression) - help with screening and assessing severity.
- Physical workup: an overactive thyroid, heart rhythm disturbances, substance misuse, and other physical causes usually have to be ruled out.
- Differentiation: anxiety disorders have to be distinguished from normal anxiety, adjustment disorders, post-traumatic stress disorder, and other mental health conditions.
More: preparing for a doctor's appointment.