Bipolar disorder:
symptoms, phases & treatment

At a glance

FrequencyAround 1–3 in 100 people are affected over the course of their life — men and women about equally often, and it usually begins between the ages of 15 and 25
Other namesManic-depressive illness, bipolar affective disorder, formerly "manic depression"
Main symptomAlternation between depressive lows and manic or hypomanic highs — with symptom-free periods in between
DiagnosisA detailed medical conversation about past mood phases — the crucial element is evidence of at least one manic or hypomanic episode
First linePhase prophylaxis with a mood stabiliser (e.g. Lithium) plus psychoeducation and a stable daily rhythm
ICD-10F31.9 (bipolar affective disorder, unspecified)

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1. What is bipolar disorder?

Bipolar disorder is a mental illness in which mood swings in phases far beyond the normal range — downwards into a depression and upwards into a mania or a milder form, hypomania. "Bipolar" means exactly that: two poles. Between the phases there are often weeks, months or years during which those affected feel completely healthy and balanced.

It is important to distinguish it from the normal mood swings that everyone knows. In bipolar disorder the phases are far more pronounced, last longer (days to months) and considerably impair everyday life, work and relationships. It is not about "sometimes in a good mood, sometimes bad", but about states that profoundly change thinking, drive, sleep and judgement.

You can picture the illness as a control system for mood and energy that has gone out of sync. In depression, drive, interest and self-worth are as if dimmed down; everyday things become a burden. In mania the opposite happens — energy, ideas and self-confidence shoot upwards, often combined with a dangerously reduced need for sleep and risky decisions. Both extremes can harm those affected and the people around them. Left untreated, the illness tends to make the phases more frequent and more intense over the years — which is why early, consistent treatment is so important.

The good news Bipolar disorder is very treatable. With effective phase prophylaxis, a stable daily rhythm and knowledge of one's own early warning signs, relapses can be reduced considerably. Many affected people lead a stable, fulfilling life — the key is that the treatment runs continuously.

2. The forms: Bipolar I and Bipolar II

Bipolar disorder is not a single, uniform illness — depending on how strong the high phases are, different forms are distinguished. The most important difference lies between a mania and a hypomania: both mean an elevated, overactive mood, but mania is much stronger, lasts longer and disrupts life massively — up to psychotic symptoms or a hospital stay.

FormHigh phaseLow phase
Bipolar IAt least one genuine mania (min. 7 days or hospital needed)Usually depressive episodes, but not required for the diagnosis
Bipolar IIHypomania (min. 4 days, without severe impairment)At least one pronounced depressive episode
CyclothymiaPersistent mild mood swings over at least 2 yearsAlternating mild highs and lows, subthreshold
Rapid cyclingAt least 4 illness phases per year — harder to treat
Table scrolls to the right

Put simply: in Bipolar I at least one severe mania is the central feature. In Bipolar II the depressive phases predominate, with milder high phases (hypomanias) in between that those affected often do not experience as pathological at all — on the contrary, they then feel especially capable and good. This is exactly what makes Bipolar II treacherous: because the highs stay inconspicuous and only the depressions are perceived as distressing, the illness is often misinterpreted as a "normal" depression.

Why the distinction matters Whether Bipolar I or II — the diagnosis helps decide the treatment. If a bipolar disorder is overlooked and treated like a pure depression, an antidepressant alone can trigger a high phase. This is why an accurate assessment by specialists is so important.

3. Symptoms: mania and depression

The symptoms depend on which phase someone is in. Characteristic is the alternation between two very opposite states — often with long, symptom-free periods in between. Sometimes signs of both poles appear at the same time; this is called a mixed episode and it is particularly distressing.

During the manic or hypomanic phase, the following typically appear:

  • Reduced need for sleep — only a few hours of sleep without feeling tired. Often one of the first and clearest warning signs.
  • Increased drive and pressure to talk — fast, jumpy speech, many ideas at once, racing thoughts.
  • Excessive self-confidence up to grandiose ideas — the feeling of being especially important, gifted or invulnerable.
  • Risky behaviour — reckless spending, risky ventures, increased risk-taking in traffic or sexually.
  • Irritability and impatience, sometimes aggressive irritability instead of euphoria.
  • In severe cases psychotic symptoms such as delusions or loss of contact with reality.

During the depressive phase, by contrast, the central features are:

  • Low mood, loss of interest and joy for most of the day.
  • Lack of drive and severe exhaustion even with small tasks.
  • Sleep problems — too little or strikingly much sleep, without feeling rested.
  • Feelings of worthlessness, guilt and hopelessness.
  • Problems with concentration and decisions, sometimes inner restlessness or thoughts of death.

The contrast is decisive: the same person who in depression can barely get out of bed in the morning may, weeks later in mania, work for days on end while losing all sense of proportion. Because many affected people do not feel ill precisely during the high phase, they usually only enter treatment during the depression — and the manic phases then go unmentioned. This is exactly why it is so important to ask actively about earlier high phases.


4. Causes & risk factors

Bipolar disorder does not arise from a single cause, but from the interplay of several factors. The most important is the hereditary predisposition: the genetic component is more pronounced here than in almost any other mental illness. Anyone with close relatives who have a bipolar disorder carries a markedly increased risk. What is inherited, however, is not the illness itself, but an increased susceptibility.¹

  • Predisposition: bipolar disorder runs strongly in families — genes play a central role.
  • Brain metabolism: an out-of-balance interplay of messenger substances such as dopamine, noradrenaline and serotonin.
  • Disrupted rhythm: lack of sleep, shift work, jet lag or an irregular daily routine can trigger phases.
  • Stress and life events: distressing upheavals, losses, but also positive excitement can be the trigger of an episode.
  • Substances: alcohol, cannabis, stimulants and some medications can promote or intensify phases.

One particular point: in bipolar disorder, sleep is not only a symptom but also a trigger. A single sleepless night can be the tipping point into a mania in sensitive people. This is why a regular sleep-wake rhythm and managing sleep disorders play such a large role in treatment. The predisposition cannot be changed — but many of the triggering factors can be influenced.


5. Diagnosis & distinguishing it from depression

The diagnosis of a bipolar disorder is made by a psychiatric or psychotherapeutic specialist — and it takes time. There is no blood test and no scan that proves the illness. The decisive element is a detailed conversation about the previous course of the mood, supplemented by questionnaires and — with consent — often also the account of relatives.¹

The key to the diagnosis is evidence of at least one manic or hypomanic episode in the past. This is exactly where the great difficulty lies: those who seek help only during depression often do not remember or mention the earlier high phases — after all, they felt like "especially good times". On average, therefore, several years pass between the first symptoms and the correct diagnosis.

  • Detailed history: when did which phases occur, how long did they last, how severe was the impairment?
  • Third-party history: relatives often perceive manic phases more clearly than those affected themselves.
  • Asking specifically about high phases: little sleep with lots of energy, pressure to talk, unusual spending, grandiose ideas.
  • Ruling out other causes: thyroid, medications, substance use and physical illnesses are clarified.
Why distinguishing it from unipolar depression is decisive If a bipolar disorder is wrongly treated as a pure (unipolar) depression, an antidepressant alone can trigger a mania or rapid cycling. This is why, before any depression treatment, one must ask actively about earlier high phases — and in bipolar disorder an antidepressant, if at all, is only used together with a mood stabiliser.

Distinguishing it from other illnesses is also part of the diagnosis: anxiety disorders, an attention disorder (ADHD), personality disorders or substance use can produce similar pictures or exist at the same time. A careful assessment is the foundation of every effective treatment.

6. Treatment: foundations, rhythm & sleep

The treatment of a bipolar disorder rests on several pillars: medication for phase prophylaxis, psychotherapy and psychoeducation, and a stable rhythm of life. None of these pillars replaces the others — only together do they unfold their full effect. The goal is not only to treat acute phases, but above all to prevent new ones.¹

A central, often underestimated building block is rhythm. Because irregular sleep and an everyday life that has gone out of sync can trigger phases, a regular daily routine is not a nice extra but effective protection. Fixed times for sleeping, getting up, eating and activity stabilise the internal clock — a principle known in the field as social rhythm therapy. The individual building blocks work together: those who combine sleep, structure and stress management noticeably lower their relapse risk.

Basis Rhythm & lifestyle — protects in every phase
Regular sleep
Fixed sleep and wake times are the single most important factor. Even one sleepless night can set off a mania in sensitive people — which is why good sleep has top priority.
Daily structure
Fixed times for meals, work and activity keep the internal clock stable. Plan major upheavals such as shift work or long-distance travel with care.
Psychoeducation
Knowing your own illness and your personal early warning signs is one of the most effective "treatments" there is. It allows you to counteract early.
Avoiding substances
Alcohol, cannabis and stimulants can trigger phases and interfere with the effect of the medication. A conscious abstention stabilises the course.

Psychotherapy — above all cognitive behavioural approaches and the rhythm therapy mentioned — helps to cope with the illness, recognise triggers and interpret early warning signs. In cases of persistent inner restlessness or sleep problems it is an important complement to medical treatment.


7. Treatment: medication explained clearly

The heart of long-term treatment is phase prophylaxis — an ongoing medication intended to prevent new highs and lows. It is usually continued even when you are doing well, because the stable state is precisely the result of the treatment. Alongside this there are medications for acute mania and for bipolar depression. Which active substance fits depends on the form, the previous course and tolerability.¹,²

First line Mood stabilisers for phase prophylaxis
Lithium
The best-evidenced mood stabiliser and often the first choice. It protects against mania and depression and demonstrably lowers the risk of suicide. Important: the blood level must be checked regularly, as the effective and the harmful range lie close together.
Particularly effective against depressive phases and therefore often used in Bipolar II. Must be introduced slowly to avoid a rare but serious skin rash.
A modern antipsychotic that works both in mania and in depression and for prevention. Typical side effects: tiredness, weight gain — often taken in the evening.
Valproate & others
Valproate works well in mania, but is not suitable for women of childbearing age. Further antipsychotics (e.g. Olanzapine, Aripiprazole) complement the treatment depending on the situation.
Antidepressants only with caution An antidepressant alone can trigger a mania or a rapid change of phases in a bipolar disorder. This is why antidepressants are used only cautiously in bipolar depression, and as a rule only together with a mood stabiliser. This is precisely the reason why the correct diagnosis is so decisive.

No medication should be stopped on your own — with Lithium in particular, an abrupt stop can provoke a new phase. Side effects are no reason to quietly stop: often a dose adjustment or a change of preparation already helps. Interactions with other agents can be checked in advance; more on this in the guide Drug interactions.

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8. Course & phase prophylaxis

Bipolar disorder is as a rule a lifelong illness that runs in phases. Between the episodes there are often long, stable periods. The goal of treatment is to make these stable phases as long as possible and to soften relapses or prevent them entirely. What this looks like in individual cases varies — which is why the therapy is tailored individually.¹

SituationTreatment goalNote
Acute maniaRapid calming, protection from harmOften an antipsychotic, hospital if needed
Bipolar depressionLift mood without triggering maniaMood stabiliser preferred
Stable phasePrevent relapses (prophylaxis)Continue medication, keep the rhythm
Rapid cyclingSlow down the change of phasesUsually avoid antidepressants
Wish to have childrenSafe choice of active substanceAvoid Valproate, plan with a specialist
Table scrolls to the right

An effective tool in the stable phase is the personal crisis plan: a list, drawn up together with treaters and relatives, of your own early warning signs and the steps that help at the start of a phase. Those who know their typical first signs — such as less sleep, more spending, an irritable mood — can counteract early, often before a full episode develops. Regular check-up appointments and documenting mood and sleep are the best foundation for this.

Spot early warning signs early

Record your mood and sleep in brite and recognise beginning phases before they overwhelm you — ideal for your next medical appointment.

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9. Everyday life & early warning signs

A large part of the treatment happens in everyday life. A few habits make the difference between stable and unstable phases:

  • Protect your sleep: keep fixed sleep times, avoid all-nighters. When sleep changes, that is often the first warning sign.
  • Track mood and sleep: short daily notes (or an app) make patterns visible and help to recognise phases early. Bring them to your appointment.
  • Medication at a fixed time: a fixed routine increases reliability. If you forget a dose, do not simply take a double one.
  • Involve relatives: people you trust often notice beginning high phases earlier than you do yourself — an agreed signal helps.
Acute crisis — get help immediately In cases of acute suicidality, thoughts of harming yourself or others (risk to others), or psychotic symptoms such as delusions or loss of contact with reality: immediately call the emergency number 112 or go to a psychiatric hospital. Available around the clock is also the Telefonseelsorge: 0800 111 0 111 or 0800 111 0 222 (free of charge, anonymous). You do not have to face a crisis alone.

How brite helps you with bipolar disorder

Bipolar disorder is not treated in weeks but over years — often with several active substances. The therapy only protects if it runs reliably and mood, sleep and early warning signs stay in view. This is exactly where brite supports you.

  • Dose reminder — Lithium, Lamotrigine, Quetiapine or your combination on time and without gaps. Set up a reminder
  • Health history — document mood, sleep and energy and bring them to your appointment as a curve. The best foundation for recognising phases early. Track the course
  • Interaction check — spots critical combinations, such as substances or medications that can trigger a phase or affect your mood stabilisers. Check now
  • Digital medication plan — all preparations clearly laid out for psychiatry, GP and pharmacy. Go to the medication plan
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FAQ: common questions about bipolar disorder

In Bipolar I, at least one genuine, severe mania occurs that massively disrupts everyday life or makes a hospital stay necessary. In Bipolar II there are only milder high phases (hypomanias), but pronounced depressive episodes. Bipolar II is often overlooked because the highs are experienced as "especially good times".
The decisive difference is the high phases: in a bipolar disorder there was at least one manic or hypomanic episode, in a unipolar depression never. This distinction is important because an antidepressant alone can trigger a mania in a bipolar disorder. This is why, before any depression treatment, one asks about earlier high phases.
Typical early warning signs are a markedly reduced need for sleep without tiredness, increased drive and pressure to talk, many ideas and racing thoughts, excessive self-confidence up to grandiose ideas, and risky behaviour such as unusual spending. Those who know their personal first signs can counteract early.
Cured in the sense of disappearing completely — as a rule it cannot be, since it is usually a lifelong illness. But it is very treatable. With effective phase prophylaxis, a stable rhythm and psychoeducation, relapses can be reduced considerably, and many affected people lead a stable, fulfilling life.
In bipolar disorder, sleep is not only a symptom but also a trigger. Even one sleepless night can set off a manic phase in sensitive people. This is why fixed sleep and wake times and a regular daily rhythm are an effective protection against new phases.
Usually yes. The phase prophylaxis is as a rule continued even in stable times, because the good state is precisely the result of the treatment. Stopping on your own is dangerous — with Lithium in particular, an abrupt stop can trigger a new phase. Always discuss changes with your treating practice.
The most important mood stabilisers are Lithium (best evidenced, also lowers the risk of suicide), Lamotrigine (above all against depressive phases) and Quetiapine (works in mania, depression and for prevention). Valproate works well in mania, but is not suitable for women who wish to have children. Which active substance fits depends on the individual course.
They can, if they are given alone. An antidepressant without a mood stabiliser can trigger a mania or a rapid change of phases (rapid cycling). This is why antidepressants are used only cautiously in bipolar depression, and mostly only in combination with a mood stabiliser — and the correct diagnosis is decisive.
In cases of acute thoughts of harming yourself or others, or psychotic symptoms such as delusions or loss of contact with reality, immediately call the emergency number 112 or go to a psychiatric hospital. Available around the clock is the Telefonseelsorge on 0800 111 0 111 or 0800 111 0 222 (free of charge, anonymous). A strongly changed mood during therapy should also be discussed quickly.

11. Related topics

Sources

  1. S3 guideline on the diagnosis and treatment of bipolar disorders (DGBS/DGPPN). awmf.org
  2. German Society for Bipolar Disorders (DGBS). dgbs.de
  3. gesundheitsinformation.de (IQWiG): Bipolar disorder. gesundheitsinformation.de
  4. Stiftung Deutsche Depressionshilfe. deutsche-depressionshilfe.de
Medical disclaimer: This article is for general information and does not replace medical or psychotherapeutic advice, diagnosis or treatment. Medication for phase prophylaxis should never be stopped on your own or changed in dose — if you have questions, contact your treating practice. In cases of acute suicidality, risk to others or psychotic symptoms, immediately call the emergency number 112 or contact the Telefonseelsorge on 0800 111 0 111 or 0800 111 0 222. Last updated: July 2026.